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Pulmonary inflammatory, chemokine, and mutagenic responses in rats after subchronic inhalation of carbon black.

Toxicology and applied pharmacology - 1 Feb 1996

Driscoll K E, Carter J M, Howard B W, Hassenbein D G, Pepelko W, Baggs R B, Oberdörster G

Abstract excerpt

Chronic inhalation of carbon black can produce carcinomas in rat lungs. At present the mechanisms underlying the rat lung tumor response to carbon black are unknown, although a significant role for inflammation and cell proliferation has been postulated. To investigate the processes which may contribute to development of rat lung tumors after carbon black exposure, we characterized the effects of subchronic...

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PMID: 8619246
DOI: 10.1006/taap.1996.0045

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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