Article
Association of thromboxane A2 receptor gene polymorphism with the phenotype of acetyl salicylic acid-intolerant asthma.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 May 2005
Kim S-H, Choi J-H, Park H-S, Holloway J W, Lee S-K, Park C-S, Shin H-D
Abstract excerpt
BACKGROUND AND OBJECTIVE: The thromboxane A2 receptor (TBXA2R) is a receptor for a potent bronchoconstrictor, TBXA2 which is known to be related to bronchial asthma and myocardial infarction. TBXA2R antagonist and TBX synthase inhibitors have been found to be effective in the management of asthmatic patients. This study was aimed to evaluate whether genetic variants of TBXA2R may be related with development of...
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