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Article

Genetic factors and insulin secretion: gene variants in the IGF genes.

Diabetes - 1 Feb 2004

't Hart Leen M, Fritsche Andreas, Rietveld Ingrid, Dekker Jacqueline M, Nijpels Giel, Machicao Fausto, Stumvoll Michael, van Duijn Cornelia M, Häring Hans U, Heine Robert J, Maassen J Antonie, van Haeften Timon W

Abstract excerpt

IGFs are important regulators of pancreatic beta-cell development, growth, and maintenance. Mutations in the IGF genes have been found to be associated with type 2 diabetes, myocardial infarction, birth weight, and obesity. These associations could result from changes in insulin secretion. We hav...

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Identifiers

PMID: 14749262
DOI: 10.2337/diabetes.53.2007.s26

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14749262-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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