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Article

INS VNTR allelic variation and dynamic insulin secretion in healthy adult non-diabetic Caucasian subjects.

Diabetic medicine : a journal of the British Diabetic Association - 1 Nov 1999

Ahmed S, Bennett S T, Huxtable S J, Todd J A, Matthews D R, Gough S C

Abstract excerpt

AIMS: To elucidate the relationship between the human insulin gene INS VNTR regulatory polymorphism and insulin secretion. The polymorphism arises from tandem repetition of 14-15 bp oligonucleotides. In Caucasians, repeat number varies from 26 to over 200, with two main and discrete allele size classes: class I (26-63 repeats) and class III (141-209 repeats). Class I allele homozygosity is associated with...

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Identifiers

PMID: 10588520
DOI: 10.1046/j.1464-5491.1999.00169.x

Genes

INS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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