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Article

Genetic and phenotypic correlations between surrogate measures of insulin release obtained from OGTT data.

Diabetologia - 1 May 2015

Gjesing Anette P, Ribel-Madsen Rasmus, Harder Marie N, Eiberg Hans, Grarup Niels, Jørgensen Torben, Ekstrøm Claus T, Pedersen Oluf, Hansen Torben

Abstract excerpt

AIMS/HYPOTHESIS: We examined the extent to which surrogate measures of insulin release have shared genetic causes. METHODS: Genetic and phenotypic correlations were calculated in a family cohort (n = 315) in which beta cell indices were estimated based on fasting and oral glucose-stimulated plasma glucose, serum C-peptide and serum insulin levels. Furthermore, we genotyped a large population-based cohort...

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PMID: 25660259
DOI: 10.1007/s00125-015-3516-9

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