Article
The biological effects of N3-methyladenine.
Journal of cellular biochemistry - 1 Feb 2004
Fronza Gilberto, Gold Barry
Abstract excerpt
The targeting of damage to DNA remains an attractive strategy to kill tumor cells. One of the serious side effects of alkylating agents is that they create both toxic (desired) and mutagenic (undesired) lesions. The result is that patients successfully treated for a primary cancer are at significant risk to develop cancer related to their therapy. To address this issue we have prepared agents that selectively...
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