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Article

Mutational analysis of neurotensin in familial restless legs syndrome.

Movement disorders : official journal of the Movement Disorder Society - 1 Jan 2004

Desautels Alex, Turecki Gustavo, Xiong Lan, Rochefort Daniel, Montplaisir Jacques, Rouleau Guy A

Abstract excerpt

A susceptibility locus for restless legs syndrome (RLS) has been identified recently on chromosome 12q. This region contains several transcribed genes including neurotensin (NTS), which, as an important modulator of the dopaminergic transmission, represents a strong functional and positional candidate in the context of RLS. In this study, NTS was evaluated for mutational analysis. A panel of 19 individuals from 4...

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Source

Identifiers

PMID: 14743366
DOI: 10.1002/mds.10617

Genes

NTS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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