Article
Association analysis of the proneurotensin gene and bipolar disorder.
Psychiatric genetics - 1 Mar 2000
Austin J, Hoogendoorn B, Buckland P, Jones I, McCandless F, Williams N, Middle F, Owen M J, Craddock N, O'Donovan M C
Abstract excerpt
Neurotensin (NT) localizes within dopaminergic neurones in the mesocortical, mesolimbic and nigrostriatal systems, and it is now clear that NT can selectively modulate dopaminergic neurotransmission. It has therefore been proposed that altered NT function might contribute to the pathogenesis of neuropsychiatric disorders in which disordered dopaminergic neurotransmission is suspected. We have previously screened...
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