Article
Eph-modulated Cell Morphology, Adhesion and Motility in Carcinogenesis
1 Jun 2005
Abstract excerpt
Eph receptor tyrosine kinases (Ephs) and their membrane anchored ephrin ligands (ephrins) form an essential cell-cell communication system that directs the positioning, adhesion and migration of cells and cell layers during development. While less prominent in normal adult tissues, there is evidence that up-regulated expression and de-regulated function of Ephs and ephrins in a large variety of human cancers may...
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