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Article

Survivin: A Bifunctional Inhibitor of Apoptosis Protein

1 Nov 2004

Abstract excerpt

Survivin is a recently discovered protein belonging to the inhibitor of apoptosis (IAP) gene family. IAP molecules are characterized by both the presence of a zinc-binding fold termed the baculoviral IAP repeat and the ability to suppress apoptosis. In addition to inhibiting apoptosis, survivin is essential for proper cell division. Survivin is expressed during embryonal development but is absent in most normal,...

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PMID: 15557069
DOI: 10.1354/vp.41-6-599

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