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Article

<i>In vivo</i> expression of survivin and its splice variant survivin‐2B: Impact on clinical outcome in acute myeloid leukemia

17 Apr 2006

Abstract excerpt

Survivin, a member of the inhibitor of apoptosis protein family, is expressed in most human cancers, but undetectable in normal differentiated adult tissue in vivo. Because of this cancer-related expression, survivin is a promising target for cancer therapy. To determine the expression and prognostic role of survivin in acute myeloid leukemia (AML), we investigated the mRNA expression pattern of survivin and of...

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PMID: 16619249
DOI: 10.1002/ijc.21995

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