Article
Chronological aging-independent replicative life span regulation by Msn2/Msn4 and Sod2 in Saccharomyces cerevisiae.
FEBS letters - 16 Jan 2004
Fabrizio P, Pletcher S D, Minois N, Vaupel J W, Longo V D
Abstract excerpt
Mutations in RAS2, CYR1, and SCH9 extend the chronological life span in Saccharomyces cerevisiae by activating stress-resistance transcription factors and mitochondrial superoxide dismutase (Sod2). Here we show that mutations in CYR1 and SCH9 also extend the replicative life span of individual yeast mother cells. However, the triple deletion of stress-resistance genes MSN2/MSN4 and RIM15, which causes a major...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.