Article
Calcium modulated signaling site in type 2 rod outer segment membrane guanylate cyclase (ROS-GC2).
Biochemical and biophysical research communications - 17 Apr 1998
Goraczniak R M, Duda T, Sharma R K
Abstract excerpt
The ROS-GC subfamily of membrane guanylate cyclases is at present represented by two members: ROS-GC1 and ROS-GC2. A unique functional feature of this subfamily is that it is intracellularly modulated in low Ca2+ concentration by calmodulin-like Ca(2+)-binding proteins termed GCAPs, 1 and 2, and the modulation is consistent with its linkage to phototransduction. The present study shows that: (1) GCAP2 is a...
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