Article
Differential activation of rod outer segment membrane guanylate cyclases, ROS-GC1 and ROS-GC2, by CD-GCAP and identification of the signaling domain.
Biochemical and biophysical research communications - 6 Jan 1998
Duda T, Goraczniak R M, Pozdnyakov N, Sitaramayya A, Sharma R K
Abstract excerpt
The ROS-GC is one of the two subfamilies of membrane guanylate cyclases. It distinguishes itself from the other surface receptor subfamily in that its members are not regulated by extracellular peptides; instead, they are modulated by intracellular Ca2+ signals. There are two members of the subfa...
Topics
- Animals
- Calcium
- Calcium-Binding Proteins
- Cattle
- Enzyme Activation
- Guanylate Cyclase
- Guanylate Cyclase-Activating Proteins
- Mutation
- Recombinant Fusion Proteins
- Rod Cell Outer Segment
- Sequence Deletion
- Vision, Ocular