Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HLA-DR15 haplotype and multiple sclerosis: a HuGE review.

American journal of epidemiology - 15 May 2007

Schmidt Hollie, Williamson Dhelia, Ashley-Koch Allison

Abstract excerpt

An association between multiple sclerosis (MS) and the human leukocyte antigen (HLA) complex, a dense cluster of genes on the short arm of chromosome 6, was first noted over 30 years ago. In Caucasian populations of Northern European descent, the DR15 haplotype (DRB1*1501-DQA1*0102-DQB1*0602) has been hypothesized to be the primary HLA genetic susceptibility factor for MS. However, studies of other populations...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Haplotypes
Share to HLA-D Antigens

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunotherapy and Immune Responses

Share to Multigene Family

Share to Multiple Sclerosis

Share to Multiple Sclerosis Research Studies

Share to T-cell and B-cell Immunology

Source

Identifiers

PMID: 17329717
DOI: 10.1093/aje/kwk118

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HLA-DR15 haplotype and multiple sclerosis: a HuGE review.PMID 17329717Read ↗

HLA-DRB5*0101 and -DRB1*1501 expression in the multiple sclerosis-associated HLA-DR15 haplotypeSemantic proximity Read ↗

Additive effect of the HLA-DR15 haplotype on susceptibility to multiple sclerosis.Semantic proximity Read ↗

Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis.Semantic proximity Read ↗

Deconstruction of HLA-DRB1*04:01:01 and HLA-DRB1*15:01:01 class II haplotypes using next-generation sequencing in European-Americans with multiple sclerosisSemantic proximity Read ↗

Genetic interaction of CTLA-4 with HLA-DR15 in multiple sclerosis patients.Semantic proximity Read ↗

Integrating risk factors: HLA-DRB1*1501 and Epstein-Barr virus in multiple sclerosis.Semantic proximity Read ↗

HLA-DRB1* allele-associated genetic susceptibility and protection against multiple sclerosis in Brazilian patientsSemantic proximity Read ↗

Analysis of HLA DR2&DQ6 (DRB1*1501, DQA1*0102, DQB1*0602) Haplotypes in Iranian Patients with Multiple SclerosisSemantic proximity Read ↗

HLA-DR15 Molecules Jointly Shape an Autoreactive T Cell Repertoire in Multiple Sclerosis.Semantic proximity Read ↗

Relationship between HLA-DRB1* 11/15 genotype and susceptibility to multiple sclerosis in Iran.Semantic proximity Read ↗

Class II HLA (DRB1, & DQB1) alleles and IL7R (rs6897932) variants and the risk for Multiple Sclerosis in Kerala, India.Semantic proximity Read ↗

HLA associations with multiple sclerosis in the Canary Islands.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.