Article

Chromogranin A regulates the dynamics of neurosecretion through its interaction with phosphatidic acid

2026-02-02

Abstract excerpt

Altered neurosecretion is a common feature of diverse pathophysiological conditions, including central nervous system disorders, hypertension, and tumorigenesis, where chromogranin A (CgA) is widely used as a biomarker, and both phosphatidic acid (PA) synthesis and catecholamine (CA) secretion are dysregulated. Here, we identify a direct interaction between CgA and PA at the plasma membrane of living cells using a...

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Literature Corpus work: 3ae346ae-419f-5a43-8d09-0ecb04138a16
DOI: 10.64898/2026.01.29.699889

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