Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neuronal peptide release is limited by secretory granule mobility.

Neuron - 1 Nov 1997

Burke N V, Han W, Li D, Takimoto K, Watkins S C, Levitan E S

Abstract excerpt

Neuropeptides are slowly released from a limited pool of secretory granules. To visualize this process, GFP-tagged preproatrial natriuretic factor (ANF) was expressed in nerve growth factor-treated PC12 cells. Biochemical and microfluorimetric experiments demonstrate that proANF-EGFP is packaged in granules that accumulate at neurite endings and is released in a Ca2+-dependent manner by secretagogs. Confocal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Kinetics
Share to Neurons
Share to Fluorescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Green Fluorescent Proteins

Share to Protein Precursors

Share to Tissue Distribution

Source

Identifiers

PMID: 9390522
DOI: 10.1016/s0896-6273(00)80400-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neuronal peptide release is limited by secretory granule mobility.PMID 9390522Read ↗

Early requirement for alpha-SNAP and NSF in the secretory cascade in chromaffin cells.Semantic proximity Read ↗

Chromogranin A regulates the dynamics of neurosecretion through its interaction with phosphatidic acidSemantic proximity Read ↗

Secretory granule biogenesis and neuropeptide sorting to the regulated secretory pathway in neuroendocrine cells.Semantic proximity Read ↗

Intracellular targeting of truncated secretory peptides in the mammalian heart and brain.Semantic proximity Read ↗

A prohormone convertase cleavage site within a predicted alpha-helix mediates sorting of the neuronal and endocrine polypeptide VGF into the regulated secretory pathway.Semantic proximity Read ↗

Sorting and activity-dependent secretion of BDNF require interaction of a specific motif with the sorting receptor carboxypeptidase e.Semantic proximity Read ↗

Visualization of neuropeptide expression, transport, and exocytosis in Drosophila melanogaster.Semantic proximity Read ↗

Kalirin/Trio Rho guanine nucleotide exchange factors regulate a novel step in secretory granule maturation.Semantic proximity Read ↗

Activity-dependent secretion of progranulin from synapsesSemantic proximity Read ↗

Visualization of Rab3A dissociation during exocytosis: a study by total internal reflection microscopy.Semantic proximity Read ↗

Imaging constitutive exocytosis with total internal reflection fluorescence microscopy.Semantic proximity Read ↗

Cytoplasmic transport signal is involved in phogrin targeting and localization to secretory granules.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.