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Article

Germinal center checkpoints in B cell tolerance in 3H9 transgenic mice.

International immunology - 1 Feb 2004

Paul Elahna, Lutz Johannes, Erikson Jan, Carroll Michael C

Abstract excerpt

Regulation throughout B cell maturation and activation prevents autoreactive B cells from entering germinal center (GC) reactions. This study shows that a subset of autoreactive B cells in V(H)3H9 micro IgH transgenic mice escapes these serial checkpoints and proceeds into splenic GC. GC B cells...

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Source

Identifiers

PMID: 14734623
DOI: 10.1093/intimm/dxh035

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14734623-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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