The germinal center: a crucible for lymphocyte selection.

doi:10.1006/smim.1996.0022

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Article

The germinal center: a crucible for lymphocyte selection.

Seminars in immunology - 1 Jun 1996

Kelsoe G

Abstract excerpt

Antigen first activates T and B lymphocytes in the T-cell areas of secondary lymphoid tissues where cognate- and costimulus-dependent proliferation expands the population of reactive lymphocytes. Selected T- and B-cell progeny from this population migrate into B-cell zones to form germinal center...

Topics

Animals
Antibody Formation
Base Sequence
Germinal Center
Humans
Lymphocyte Activation
Molecular Sequence Data
Mutation
T-Lymphocytes

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