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Article

Differential downregulation of endoplasmic reticulum-residing chaperones calnexin and calreticulin in human metastatic melanoma.

Cancer letters - 20 Jan 2004

Dissemond Joachim, Busch Michael, Kothen Thomas, Mörs Janet, Weimann Tatjana K, Lindeke Anette, Goos Manfred, Wagner Stephan N

Abstract excerpt

Characterization of the molecular basis of tumor recognition by T cells has shown that major histocompatibility complex (MHC) class I molecules play a crucial role in presenting antigenic peptide epitopes to cytotoxic T lymphocytes. MHC class Ia downregulation has been repeatedly described on melanoma cells and is thought to be involved in the failure of the immune system to control tumor progression. Proper...

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Source

Identifiers

PMID: 14732231
DOI: 10.1016/j.canlet.2003.09.036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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