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Article

Biosynthesis of HLA-C heavy chains in melanoma cells with multiple defects in the expression of HLA-A, -B, -C molecules.

British journal of cancer - 1 May 1999

Martayan A, Fraioli R, Giorda E, Setini A, Ciccarelli G, Delfino L, Ferrara G B, Giacomini P

Abstract excerpt

Recent investigations have shown that malignant transformation may down-regulate the expression of class I HLA molecules, beta2-microglobulin (beta2m) and members of the antigen-processing machinery. In the present study, we HLA-genotyped and identified at a biochemical level the three (HLA-A25, -B8, -Cw7) class I alleles expressed by the previously described [D'Urso CM et al (1992) J Clin Invest 87: 284-292]...

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Identifiers

PMID: 10360639
DOI: 10.1038/sj.bjc.6690405
PMCID: PMC2362293

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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