Article
Calnexin recognizes carbohydrate and protein determinants of class I major histocompatibility complex molecules.
The Journal of biological chemistry - 24 Feb 1995
Zhang Q, Tector M, Salter R D
Abstract excerpt
Proper folding of nascent polypeptides is essential for their function and is monitored by intracellular "quality control" elements. The molecular chaperone calnexin participates in this process by retaining in the endoplasmic reticulum a variety of unfolded proteins, including class I major hist...
Topics
- Calcium-Binding Proteins
- Calnexin
- Carbohydrate Metabolism
- Cell Line
- Genes, MHC Class I
- HLA-A2 Antigen
- HLA-B7 Antigen
- Humans
- Indolizines
- Mutation
- Polysaccharides
- Protein Binding
- Proteins
- Temperature