Article
Analysis of Snu13p mutations reveals differential interactions with the U4 snRNA and U3 snoRNA.
RNA (New York, N.Y.) - 1 Feb 2004
Dobbyn Helen C, O'Keefe Raymond T
Abstract excerpt
Pre-mRNA splicing is executed by the spliceosome, a complex of small nuclear RNAs (snRNAs) and numerous proteins. One such protein, 15.5K/Snu13p, is associated with the spliceosomal U4/U6.U5 tri-snRNP and box C/D small nucleolar ribonucleoprotein particles (snoRNPs), which act during preribosomal RNA (rRNA) processing. As such, it is the first splicing factor to be identified in two functionally distinct...
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