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Article

Preβ high density lipoprotein has two metabolic fates in human apolipoprotein A-I transgenic mice

12 Mar 2004

Abstract excerpt

We compared the in vivo metabolism of prebeta HDL particles isolated by anti-human apolipoprotein A-I (apoA-I) immunoaffinity chromatography (LpA-I) in human apoA-I transgenic (hA-I Tg) mice with that of lipid-free apoA-I (LFA-I) and small LpA-I. After injection, prebeta LpA-I were removed from plasma more rapidly than were LFA-I and small LpA-I. Prebeta LpA-I and LFA-I were preferentially degraded by kidney...

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Identifiers

PMID: 14729861
DOI: 10.1194/jlr.m300422-jlr200

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