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Article

High density lipoprotein particle size restriction in apolipoprotein A-I(Milano) transgenic mice.

Journal of lipid research - 1 Nov 1997

Bielicki J K, Forte T M, McCall M R, Stoltzfus L J, Chiesa G, Sirtori C R, Franceschini G, Rubin E M

Abstract excerpt

Human carriers of apolipoprotein A-I(Milano) (Arg173 --> Cys substitution in apolipoprotein A-I) are characterized by an HDL deficiency in which small, dense HDL accumulate in plasma. Because affected individuals are heterozygous for this mutation, the full impact of apolipoprotein A-I(Milano) (apoA-I(Milano)) on HDL-cholesterol metabolism is unknown. In this study, apoA-I(Milano) transgenic mice were used to...

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PMID: 9392429

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LCAT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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