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Proteomic and functional analysis of HDL subclasses in humans and rats: a proof-of-concept study

29 Jun 2023

Abstract excerpt

BACKGROUND: The previous study investigated whether the functions of small, medium, and large high density lipoprotein (S/M/L-HDL) are correlated with protein changes in mice. Herein, the proteomic and functional analyses of high density lipoprotein (HDL) subclasses were performed in humans and rats. METHODS: After purifying S/M/L-HDL subclasses from healthy humans (n = 6) and rats (n = 3) using fast protein...

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PMID: 37386457
DOI: 10.1186/s12944-023-01829-9

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