The distinct metabolism between large and small HDL indicates unique origins of human apolipoprotein A4

Abstract excerpt

Apolipoprotein A4's (APOA4's) functions on HDL in humans are not well understood. A unique feature of APOA4 is that it is an intestinal apolipoprotein secreted on HDL and chylomicrons. The goal of this study was to gain a better understanding of the origin and function of APOA4 on HDL by studying its metabolism across 6 HDL sizes. Twelve participants completed a metabolic tracer study. HDL was isolated by APOA1...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Diabetes, Cardiovascular Risks, and Lipoproteins
• Share to Diabetes Treatment and Management
• Share to Lipid metabolism and disorders