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Article

Effects of E-cadherin (CDH1) gene promoter polymorphisms on the risk and clinicopathological development of hepatocellular carcinoma.

Journal of surgical oncology - 1 Sept 2011

Chien Ming-Hsien, Yeh Kun-Tu, Li Yi-Ching, Hsieh Yi-Hsien, Lin Chien-Huang, Weng Meng-Shih, Kuo Wu-Hsien, Yang Shun-Fa

Abstract excerpt

BACKGROUND AND OBJECTIVES: Hepatocellular carcinoma (HCC) is one of the most frequent malignant neoplasms worldwide, and is the second leading cause of cancer death in Taiwan. E-cadherin is an epithelial cell adhesion molecule, and decreased E-cadherin expression in HCC is associated with a poor prognosis. This study investigates the effects of single nucleotide polymorphisms (SNPs) in the E-cadherin/CDH1 gene...

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Source

Identifiers

PMID: 21462191
DOI: 10.1002/jso.21929

Genes

CDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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