Article
Correlation of a single nucleotide polymorphism in the E-cadherin gene promoter with tumorigenesis and progression of gastric carcinoma in Japan.
International journal of oncology - 1 Aug 2003
Kuraoka Kazuya, Oue Naohide, Yokozaki Hiroshi, Kitadai Yasuhiko, Ito Reiko, Nakayama Hirofumi, Yasui Wataru
Abstract excerpt
A C/A single nucleotide polymorphism (SNP) in the E-cadherin gene promoter has been shown to affect transcriptional efficiency in vitro. In this study, we analyzed the C/A SNP in 106 gastric carcinoma cases and 90 cancer-free controls compared with clinicopathological parameters. The genotype of...
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