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Article

Identification of a novel gene family that includes the interferon-inducible human genes 6–16 and ISG12

19 Jan 2004

Abstract excerpt

BACKGROUND: The human 6-16 and ISG12 genes are transcriptionally upregulated in a variety of cell types in response to type I interferon (IFN). The predicted products of these genes are small (12.9 and 11.5 kDa respectively), hydrophobic proteins that share 36% overall amino acid identity. Gene disruption and over-expression studies have so far failed to reveal any biochemical or cellular roles for these...

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PMID: 14728724
DOI: 10.1186/1471-2164-5-8

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