Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

LRP5, low-density-lipoprotein-receptor-related protein 5, is a determinant for bone mineral density.

Journal of human genetics - 1 Jan 2004

Mizuguchi Takeshi, Furuta Itsuko, Watanabe Yukio, Tsukamoto Kazuhiro, Tomita Hiroshi, Tsujihata Mitsuhiro, Ohta Tohru, Kishino Tatsuya, Matsumoto Naomichi, Minakami Hisanori, Niikawa Norio, Yoshiura Koh-Ichiro

Abstract excerpt

Osteoporosis is a multifactorial trait with low bone mineral density (BMD). We report results of an association study between BMD and nine candidate genes ( TGFB1, TGFBR2, SMAD2, SMAD3, SMAD4, IFNB1, IFNAR1, FOS and LRP5), as well as of a case-control study of osteoporosis. Samples for the former...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Density
Share to Japan
Share to LDL-Receptor Related Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Linkage Disequilibrium

Share to Low Density Lipoprotein Receptor-Related Protein-5

Share to Osteoporosis

Share to Receptors, LDL

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 14727154
DOI: 10.1007/s10038-003-0111-6

Genes

LRP5
FOS
IFNAR1
IFNB1
SMAD2
SMAD3
SMAD4
TGFB1
TGFBR2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14727154-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

LRP5, low-density-lipoprotein-receptor-related protein 5, is a determinant for bone mineral density.PMID 14727154Read ↗

Association of a single-nucleotide polymorphism in low-density lipoprotein receptor-related protein 5 gene with bone mineral density.Semantic proximity Read ↗

Common polymorphism in the LRP5 gene may increase the risk of bone fracture and osteoporosis.Semantic proximity Read ↗

Association between LRP5 polymorphism and bone mineral density: a Bayesian meta-analysis.Semantic proximity Read ↗

Association of a single-nucleotide variation (A1330V) in the low-density lipoprotein receptor-related protein 5 gene (LRP5) with bone mineral density in adult Japanese women.Semantic proximity Read ↗

Low-density lipoprotein receptor-related protein 5 (LRP5) gene polymorphisms are associated with bone mass in both Chinese and whites.Semantic proximity Read ↗

Polymorphism of LRP5, but not of TNFRSF11B, is associated with a decrease in bone mineral density in postmenopausal Maya-Mestizo women.Semantic proximity Read ↗

LRP5 and bone mass regulation: Where are we now?Semantic proximity Read ↗

Relationship between polymorphisms and mutations at rs7125942 and rs3736228 of LRP5 gene and bone metabolism in postmenopausal women.Semantic proximity Read ↗

Association of rs3736228 polymorphism in LRP5 gene with bone fracture and osteoporosis: a systematic review and updated meta-analysisSemantic proximity Read ↗

Bone growth gene may lead to new osteoporosis treatments. The Lrp5 gene aids in bone growth and strength as well as bone deterioration, depending on certain mutations.Semantic proximity Read ↗

The importance of the Wnt/β-catenin pathway and LRP5 protein in bone metabolism of postmenopausal women.Semantic proximity Read ↗

Functional relevance of the BMD-associated polymorphism rs312009: novel involvement of RUNX2 in LRP5 transcriptional regulation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.