Article
MTHFR c.677C>T polymorphism as an independent predictor of peak bone mass in Danish men--results from the Odense Androgen Study.
Bone - 1 Feb 2006
Abrahamsen Bo, Jørgensen Henrik L, Nielsen Torben L, Andersen Marianne, Haug Egil, Schwarz Peter, Hagen Claus, Brixen Kim
Abstract excerpt
The MTHFR c.677C>T polymorphism has been shown to have significant effects on skeletal health in middle-aged to elderly women and men. Despite an accumulating amount of data on MTHFR genetics and the association between homocysteine levels and fracture, it remains unknown if MTHFR c.677C>T genoty...
Topics
- Absorptiometry, Photon
- Adult
- Bone Density
- Bone and Bones
- Denmark
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Hip
- Humans
- Lumbar Vertebrae
- Male
- Methylenetetrahydrofolate Reductase (NADPH2)
- Polymorphism, Genetic
- Polymorphism, Single Nucleotide
- Prospective Studies
- Spine