Article
MTHFR c.677C>T polymorphism as an independent predictor of peak bone mass in Danish men--results from the Odense Androgen Study.
Bone - 1 Feb 2006
Abrahamsen Bo, Jørgensen Henrik L, Nielsen Torben L, Andersen Marianne, Haug Egil, Schwarz Peter, Hagen Claus, Brixen Kim
Abstract excerpt
The MTHFR c.677C>T polymorphism has been shown to have significant effects on skeletal health in middle-aged to elderly women and men. Despite an accumulating amount of data on MTHFR genetics and the association between homocysteine levels and fracture, it remains unknown if MTHFR c.677C>T genotype affects bone mineral accretion in youth or bone loss in adulthood. The purpose of this cross-sectional study was to...
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