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Article

Impaired neuromuscular transmission and skeletal muscle fiber necrosis in mice lacking Na/Ca exchanger 3.

The Journal of clinical investigation - 1 Jan 2004

Sokolow Sophie, Manto Mario, Gailly Philippe, Molgó Jordi, Vandebrouck Clarisse, Vanderwinden Jean-Marie, Herchuelz Andre, Schurmans Stéphane

Abstract excerpt

We produced and analyzed mice deficient for Na/Ca exchanger 3 (NCX3), a protein that mediates cellular Ca(2+) efflux (forward mode) or Ca(2+) influx (reverse mode) and thus controls intracellular Ca(2+) concentration. NCX3-deficient mice (Ncx3(-/-)) present a skeletal muscle fiber necrosis and a...

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Identifiers

PMID: 14722618
DOI: 10.1172/JCI18688
PMCID: PMC310749

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-14722618-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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