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Article

Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.

The EMBO journal - 3 Jul 1995

Takeshima H, Yamazawa T, Ikemoto T, Takekura H, Nishi M, Noda T, Iino M

Abstract excerpt

While subtypes 1 and 2 of the ryanodine receptor (RyR) function as intracellular Ca2+ release channels, little is known about the function of the third subtype (RyR-3), first identified in brain. Myocytes from mice homozygous for a targeted mutation in the RyR-1 gene (dyspedic mice) can now be used for a study on the function of RyR-3, which is predominantly expressed in these cells according to our reverse...

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Identifiers

PMID: 7621815
DOI: 10.1002/j.1460-2075.1995.tb07302.x
PMCID: PMC394359

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Source receipt: pubmed, retrieved 7 Sept 2026.

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