Article
Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.
The EMBO journal - 3 Jul 1995
Takeshima H, Yamazawa T, Ikemoto T, Takekura H, Nishi M, Noda T, Iino M
Abstract excerpt
While subtypes 1 and 2 of the ryanodine receptor (RyR) function as intracellular Ca2+ release channels, little is known about the function of the third subtype (RyR-3), first identified in brain. Myocytes from mice homozygous for a targeted mutation in the RyR-1 gene (dyspedic mice) can now be us...
Topics
- Adenine Nucleotides
- Amino Acid Sequence
- Animals
- Base Sequence
- Binding Sites
- Caffeine
- Calcium
- Calcium Channels
- Calmodulin-Binding Proteins
- Cells, Cultured
- Mice
- Mice, Mutant Strains
- Molecular Sequence Data
- Muscle Proteins
- Muscles
- Mutation
- Ryanodine
- Ryanodine Receptor Calcium Release Channel