Article
Roles of Na(+)/Ca(2+) exchanger isoforms NCX1 and NCX2 in motility in mouse ileum.
Naunyn-Schmiedeberg's archives of pharmacology - 1 Oct 2016
Nishiyama Kazuhiro, Azuma Yasu-Taka, Morioka Ai, Yoshida Natsuho, Teramoto Midori, Tanioka Kohta, Kita Satomi, Hayashi Satomi, Nakajima Hidemitsu, Iwamoto Takahiro, Takeuchi Tadayoshi
Abstract excerpt
The Na(+)/Ca(2+) exchanger (NCX) is a plasma membrane transporter that is involved in regulating intracellular Ca(2+) concentrations in various tissues. The physiological roles by which NCX influences gastrointestinal motility are incompletely understood, although its role in the heart, brain, and kidney has been widely investigated. In this study, we focused on the functions of the NCX isoforms, NCX1 and NCX2,...
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