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Article

New functional sites in MutS affect DNA mismatch repair.

Science China. Life sciences - 1 Oct 2010

Zhong Tianying, Bi Lijun, Zhang Xianen

Abstract excerpt

The MutS protein plays an important role in the DNA mismatch repair system. Mutations in the mutS gene can lead to genome instability and ultimately cell malfunction. Here we have established a method for identifying functional defective mutants of MutS by random mutation and rifampicin screening. Some novel functional sites in MutS were identified. The MutS mutant strains were analyzed using surface plasmon...

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Source

Identifiers

PMID: 20953938
DOI: 10.1007/s11427-010-4065-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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