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Article

Trinucleotide-repeat expanded and normal DMPK transcripts contain unusually long poly(A) tails despite differential nuclear residence.

Biochimica et biophysica acta. Gene regulatory mechanisms - 1 Jun 2017

Gudde Anke E E G, van Kessel Ingeborg D G, André Laurène M, Wieringa Bé, Wansink Derick G

Abstract excerpt

In yeast and higher eukaryotes nuclear retention of transcripts may serve in control over RNA decay, nucleocytoplasmic transport and premature cytoplasmic appearance of mRNAs. Hyperadenylation of RNA is known to be associated with nuclear retention, but the cause-consequence relationship between hyperadenylation and regulation of RNA nuclear export is still unclear. We compared polyadenylation status between...

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Source

Identifiers

PMID: 28435090
DOI: 10.1016/j.bbagrm.2017.04.002

Genes

DMPK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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