Article
Determinants of Rbp1p localization in specific cytoplasmic mRNA-processing foci, P-bodies.
The Journal of biological chemistry - 29 Sept 2006
Jang Li-Ting, Buu Leh-Miauh, Lee Fang-Jen S
Abstract excerpt
Rbp1p, a yeast RNA-binding protein, decreases the level of mitochondrial porin mRNA by enhancing its degradation, but the intracellular location of the Rbp1p-mediated degradation complex remains unknown. We show here that Rbp1p in xrn1Delta mutant yeast localizes in specific cytoplasmic foci that are known as P-bodies. The N-terminal and RNA recognition motif (RRM) 1 domains of Rbp1p are necessary but not...
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