Article

Low fidelity DNA polymerase IV accelerates genome evolution in <i>Pseudomonas aeruginosa</i>

2024-10-24

Abstract excerpt

<h4>ABSTRACT</h4> Specialized DNA polymerases are crucial for bypassing lesions and facilitating various cellular processes. Despite extensive research, the mutagenic effects of these error-prone enzymes on genomes are still not fully understood. In this study, we examined the genomic instability caused by Pol IV in the bacterial pathogen Pseudomonas aeruginosa . Pol IV mutagenesis primarily involved the misinco...

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Literature Corpus work: 83d1b901-736f-5aad-a379-2ee277f0fd70
DOI: 10.1101/2024.10.22.619742

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