Article
Evaluation of liquid biopsies for detection of emerging mutated genes in metastatic colorectal cancer.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology - 1 Jul 2018
Furuki Hiroyasu, Yamada Takeshi, Takahashi Goro, Iwai Takuma, Koizumi Michihiro, Shinji Seiichi, Yokoyama Yasuyuki, Takeda Kohki, Taniai Nobuhiko, Uchida Eiji
Abstract excerpt
BACKGROUND: Detection of gene mutations is important for planning molecular targeted therapy. Although most gene mutations are concordant between primary colon cancers and their liver metastases, new mutations can emerge in metastases. The liquid biopsy is a newly developed, gene analytic method to detect mutations in metastatic tumors. In this prospective study, we evaluated the applicability of liquid biopsies...
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