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Article

Improved marker combination for detection of de novo genetic variation and aberrant DNA in colorectal neoplasia.

Clinical chemistry - 1 Dec 2006

Kann Lisa, Han James, Ahlquist David, Levin Theodore, Rex Douglas, Whitney Duncan, Markowitz Sanford, Shuber Anthony

Abstract excerpt

BACKGROUND: The genetic heterogeneity of sporadic colorectal cancer (CRC) makes the choice of genetic markers and sequence variation-detection technologies critical to the performance of screening assays. We have previously described the effectiveness of a CRC assay composed of 22 known variants...

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Source

Identifiers

PMID: 17082247
DOI: 10.1373/clinchem.2007.070896

Genes

APC
BRAF
CTNNB1
VIM
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17082247-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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