Article
Traf6 is essential for murine tooth cusp morphogenesis.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jan 2004
Ohazama Atsushi, Courtney Jo-Maree, Tucker Abigail S, Naito Asuka, Tanaka Sakae, Inoue Jun-Ichiro, Sharpe Paul T
Abstract excerpt
Ectodermal appendages such as skin, hair, teeth, and sweat glands are affected in patients with hypohidrotic (anhydrotic) ectodermal dysplasia (HED). It has been established that mutations in the tumor necrosis factor (TNF) superfamily of molecules, i.e., ectodysplasin (EDA), EDA receptor (EDAR), and EDAR-associated death domain (EDARADD; the intracellular adaptor for EDAR), are responsible for several forms of...
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