Involvement of a novel Tnf receptor homologue in hair follicle induction.

doi:10.1038/11943

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Article

Involvement of a novel Tnf receptor homologue in hair follicle induction.

Nature genetics - 1 Aug 1999

Headon D J, Overbeek P A

Abstract excerpt

Although inductive interactions are known to be essential for specification of cell fate in many vertebrate tissues, the signals and receptors responsible for transmitting this information remain largely unidentified. Mice with mutations in the downless (dl) gene have defects in hair follicle induction, lack sweat glands and have malformed teeth. These structures originate as ectodermal placodes, which invaginate...

Topics

Amino Acid Sequence
Animals
Bone Morphogenetic Protein 4
Bone Morphogenetic Proteins
Cloning, Molecular
Ectodysplasins
Edar Receptor
Hair Follicle
Hedgehog Proteins
Humans
Membrane Proteins
Mice
Models, Genetic
Molecular Sequence Data
Phenotype
Proteins
Receptors, Ectodysplasin
Receptors, Tumor Necrosis Factor

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Identifiers

PMID: 10431242
DOI: 10.1038/11943

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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