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Article

Effective scoring function for protein sequence design.

Proteins - 1 Feb 2004

Liang Shide, Grishin Nick V

Abstract excerpt

We have developed an effective scoring function for protein design. The atomic solvation parameters, together with the weights of energy terms, were optimized so that residues corresponding to the native sequence were predicted with low energy in the training set of 28 protein structures. The solvation energy of non-hydrogen-bonded hydrophilic atoms was considered separately and expressed in a nonlinear way. As a...

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Identifiers

PMID: 14696189
DOI: 10.1002/prot.10560

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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