Article

B-SIDER: Computational Algorithm for the Design of Complementary β-sheet Sequences

2019-05-09

Abstract excerpt

The β-sheet is an element of protein secondary structure, and intra-/inter-molecular β-sheet interactions play pivotal roles in biological regulatory processes including scaffolding, transporting, and oligomerization. In nature, a β-sheet formation is tightly regulated because dysregulated β-stacking often leads to severe diseases such as Alzheimer’s, Parkinson’s, systemic amyloidosis, or diabetes. Thus, the ident...

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Literature Corpus work: 352cb5b3-2757-5c21-95f0-8a0c380d80fe
DOI: 10.1101/631069

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