Article
Variants in TNFRSF5 locus and association analysis with Hepatitis B virus (HBV) infection.
Human mutation - 1 Jan 2004
Zhou Gangqiao, Zhai Yun, Dong Xiaojia, Li Ya, Zhang Xiumei, Zhang Ruifang, Li Shuqing, Li Xuhong, He Fengying, Wei Handong, Chen Xiaoping, Yao Zhijian, Shen Yan, Qiang Boqing, He Fuchu
Abstract excerpt
Human TNFRSF5, a key signaling molecule expressed by antigen-presenting cells of the immune system, might have associations with autoimmune diseases and various infectious diseases. In the present study, we screened single-nucleotide polymorphisms (SNPs) in TNFRSF5 and examined whether they are risk factors for persistent HBV infection or disease severity. We resequenced all 9 exons, the promoter and splicing...
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