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Article

Genetic variants of interferon regulatory factor 5 associated with chronic hepatitis B infection.

World journal of gastroenterology - 14 Jan 2018

Sy Bui Tien, Hoan Nghiem Xuan, Tong Hoang Van, Meyer Christian G, Toan Nguyen Linh, Song Le Huu, Bock Claus-Thomas, Velavan Thirumalaisamy P

Abstract excerpt

AIM: To investigate possible effects of IRF5 polymorphisms in the 3' UTR region of the IFR5 locus on susceptibility to hepatitis B virus (HBV) infection and progression of liver diseases among clinically classified Vietnamese patients. METHODS: Four IFR5 SNPs (rs13242262A/T, rs77416878C/T, rs10488630A/G, and rs2280714T/C) were genotyped in clinically classified HBV patients [chronic hepatitis B (CHB). n = 99;...

Topics

3' Untranslated Regions
Adolescent
Adult
Aged
Carcinoma, Hepatocellular
Case-Control Studies
Disease Progression
Female
Gene Frequency
Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Predisposition to Disease

Haplotypes

Hepatitis B, Chronic

Humans

Interferon Regulatory Factors

Liver Cirrhosis

Liver Neoplasms

Logistic Models

Source

Open in PubMed Open full text

Identifiers

PMID: 29375210
DOI: 10.3748/wjg.v24.i2.248
PMCID: PMC5768943

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-29375210-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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