Article
[Association of TNFA polymorphisms with the outcomes of HBV infection].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Aug 2005
Liu Ying, Guo Xin-hui, Du Te, Li Jun-hong, Zhu Xi-lin, Gao Ji-rong, Lu Liang-ping, Gou Chun-yan, Li Zhuo, Li Hui
Abstract excerpt
OBJECTIVE: To explore whether the TNFA promoter single nucleotide polymorphisms (SNPs) are associated with the outcomes of hepatitis B virus(HBV) infection in Chinese Han population. METHODS: One hundred and forty-eight self-limited HBV infection subjects and 207 chronic hepatitis B patients were recruited. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and sequence specific...
Topics
- Adult
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Haplotypes
- Hepatitis B
- Humans
- Male
- Middle Aged
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Polymorphism, Single Nucleotide
