Article
Expression quantitative trait loci for TNFRSF10 influence both HBV infection and hepatocellular carcinoma development.
Journal of medical virology - 1 Mar 2016
Wen Juan, Song Ci, Liu Jibin, Chen Jianguo, Zhai Xiangjun, Hu Zhibin
Abstract excerpt
Tumor necrosis factor receptor superfamily member 10 (TNFRSF10) is a death domain-containing receptor for the apoptotic ligand TNFSF10, which involves multiple processes, including hepatocarcinogenesis and immune response against HBV infection. Several single nucleotide polymorphisms (SNPs) were identified as expression quantitative trait loci (eQTLs) for TNFRSF10. To assess the association of TNFRSF10 eQTL SNPs...
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