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Article

Family-based tests for associating haplotypes with general phenotype data: application to asthma genetics.

Genetic epidemiology - 1 Jan 2004

Horvath Steve, Xu Xin, Lake Stephen L, Silverman Edwin K, Weiss Scott T, Laird Nan M

Abstract excerpt

We provide a general purpose family-based testing strategy for associating disease phenotypes with haplotypes when phase may be ambiguous and parental genotype data may be missing. These tests for linkage and association can be used in candidate gene studies with tightly linked markers. Our proposed weighted conditional approach extends the method described in Rabinowitz and Laird to multiple markers. It is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14691957
DOI: 10.1002/gepi.10295

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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